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目的:分析不同类型围手术期患者抗菌药物的预防性使用情况。方法:选取2013年11月—2014年10月间住院治疗的Ⅰ、Ⅱ、Ⅲ类切口手术患者600例作为研究对象;对这600例围手术期患者临床预防性使用抗菌药物的情况进行回顾性分析,分析临床使用抗菌药物的现状,包括使用频率、使用时间、给药时间和联合用药情况等,以及对预防性使用抗菌药物的适应证、给药时间、手术中追加使用、手术后使用、选药方面的合理性,针对其中的弊端,制订相应的管理措施。结果:Ⅰ类切口患者抗菌药物的使用概率为72.50%,Ⅱ类切口患者抗菌药物的使用率为100.00%,Ⅲ类切口患者使用抗菌药物的使用率为100.00%;术后使用抗菌药物的使用率普遍偏高,均超过了50.00%;单种抗菌药物的使用率为最高;围手术期患者抗菌药物的使用存在不合理性。结论:对围手术期的患者预防性使用抗菌药物时,需要做到加强管理,以保证临床使用抗菌药物的合理性,保障患者的生命安全。
OBJECTIVE: To analyze the prophylactic use of antimicrobial agents in different types of perioperative patients. Methods: A total of 600 patients with type Ⅰ, Ⅱ, Ⅲ incision in hospital from November 2013 to October 2014 were selected as the research object. The clinical data of 600 patients with perioperative prophylaxis using antibiotics were retrospectively analyzed Analysis and analysis of the status quo of clinical use of antimicrobial drugs, including frequency of use, time of use, time of administration and combination of drug use, as well as indications for prophylactic use of antimicrobial agents, administration time, additional use in surgery, postoperative use, The rationality of drug selection, in view of the drawbacks, to formulate the appropriate management measures. Results: The incidence of antimicrobial agents in type Ⅰ incision patients was 72.50%, that of type Ⅱ incision patients was 100.00%, and that of type Ⅲ incision patients was 100.00%. The usage of antibacterials Generally higher than 50.00%; the use rate of single antibacterials was the highest; the use of antibacterials in perioperative patients was unreasonable. Conclusion: When prophylactic use of antimicrobial agents in perioperative patients, we need to strengthen management to ensure the rational use of antimicrobial agents in clinical practice and ensure the patient’s life safety.