低场强MR成像在胃癌诊断中的应用研究

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目的:探讨低场强MR成像技术在胃癌诊断中的作用。材料与方法:50例正常成人服用不同量的水和造影剂(GdDTPA)溶液、空气,注射或不注射低张药物后,进行多方位、多系列MR增强前后扫描以资对照。30例进展期胃癌患者,空腹4~8小时,检查前10分钟肌注654220mg,检查前即刻喝水600~1000ml,行多方位、多系列增强前后扫描。18例手术患者,术前进行TNM分期和可切除性评估。结果:MRI可清晰显示胃的解剖结构,邻近器官的毗邻关系;正常胃壁厚度与胃充盈的程度和扩张关系密切,在不同部位胃壁的厚度也不一致,在适度充盈下,正常胃壁厚度<4~6mm,正常胃壁的MRI信号均匀一致,T1WI、T2WI均呈等信号,GRL呈稍高信号,增强扫描,轻度均匀强化。进展期胃癌MRI检出率为100%。胃癌的MRI分期准确性94.5%,术前可切除性估价的准确性为89%。结论:MRI能清晰显示胃壁的厚度、解剖结构和毗邻关系。在进展期胃癌的诊断中,MRI不仅能显示胃腔内外和胃壁内肿块、胃壁增厚、邻近器官的侵犯,还能显示淋巴结肿大,肝、脾、胰、网膜、腹腔的转移。其异常信号改变颇具特异性。MRI在进展期胃癌的诊断、分期和术前评估等方面具? Objective: To investigate the role of low-field MR imaging in the diagnosis of gastric cancer. Materials and Methods: 50 healthy adults were given various doses of water and contrast medium (Gd  DTPA) solution and air. After injection or non-injection of hypotensive drugs, multi-faceted and multi-series MR scans were performed before and after contrast for comparison. 30 cases of advanced gastric cancer patients, fasting 4 to 8 hours, 10 minutes before the examination intramuscular injection of 654 220mg, immediately before the inspection of drinking water 600 ~ 1000ml, multi-directional, multi-series enhanced before and after the scan. In 18 surgical patients, preoperative TNM staging and resectability were evaluated. Results: MRI can clearly show the anatomical structure of the stomach and the adjoining relationship between adjacent organs. The normal wall thickness is closely related to the extent and dilatation of the gastric filling, and the thickness of the stomach wall is also different at different sites. Under moderate filling, the normal stomach wall thickness is <4~ 6mm, normal MRI signal of the stomach wall was uniform, T1WI, T2WI showed equal signal, GRL was slightly higher signal, enhanced scan, mild evenly enhanced. The MRI detection rate of advanced gastric cancer was 100%. The accuracy of MRI staging of gastric cancer was 94.5%, and the accuracy of preoperative resectability assessment was 89%. Conclusion: MRI can clearly show the thickness, anatomical structure, and the adjacent relationship of the stomach wall. In the diagnosis of advanced gastric cancer, MRI can not only show the inside and outside of the stomach cavity and the gastric wall mass, thickening of the stomach wall, invasion of adjacent organs, but also shows lymph node enlargement, liver, spleen, pancreas, retina, and abdominal cavity. The abnormal signal change is quite specific. MRI is useful in the diagnosis, staging, and preoperative assessment of advanced gastric cancer?
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