【摘 要】
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目的 观察光动力疗法(PDT)治疗中心性渗出性脉络膜视网膜病变(CEC)的临床疗效及安全性.方法 回顾28例经眼底检查、荧光素眼底血管造影(FFA)及光相干断层扫描(OCT)确诊的CEC患
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目的 观察光动力疗法(PDT)治疗中心性渗出性脉络膜视网膜病变(CEC)的临床疗效及安全性.方法 回顾28例经眼底检查、荧光素眼底血管造影(FFA)及光相干断层扫描(OCT)确诊的CEC患者28只患眼PDT治疗前后的临床资料,对比分析治疗前后的视力、眼底像、FFA及OCT检查结果,统计重复治疗的次数,观察治疗的安全性.28例患者平均年龄31.5岁,就诊时最佳矫正视力0.02～0.8.28只眼共治疗38次,其中,22只眼治疗1次,3只眼治疗2次,2只眼治疗3次,1只眼治疗4次.PDT治疗后平均随访时间26个月.结果 PDT治疗后末次随访时,视力提高≥2行的视力明显改善者21只眼,占75.00%;视力波动在1行以内的视力稳定者5只眼,占17.86%;视力下降≥2行的视力下降者2只眼,占7.14%.FFA检查显示:21只眼CNV完全闭合,占75.00%;3只眼CNV部分闭合,占10.71%;4只眼CNV未闭合或CNV扩大,占14.29%.有6只眼出现视网膜色素上皮损害,占21.43%.结论 PDT治疗CEC对于大多数患者是安全有效的,对于小病变,可以适当减小光斑治疗;对于一次治疗效果不佳的患者,重复治疗应考虑其病因.
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