【摘 要】
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Cellular senescence is an irreversible cell cycle arrest triggered by the activation of oncogenes or mitogenic signaling as well as the enforced expression of t
【机 构】
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DepartmentofImmunology,DivisionofCancerBiology,DivisionofMolecularRadiationBiology,SectionofBacteria
【基金项目】
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We thank Drs. Bert Vogelstein for p53 +/+ and -/- HCTll6 cell lines, Yoshimi Takai for human H-rasv12 cDNA, and Ryuji Higashikubo for critical reading of the manuscript. This work was partly supported