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目的研究不同糖代谢状态下C反应蛋白水平。方法用速率比浊法测定慢性持续性高血糖组、慢性波动性高血糖组、空腹血糖受损组、糖耐量异常组和正常血糖组CRP水平。结果波动性高血糖组CRP明显高于持续性高血糖组,空腹血糖受损组与糖耐量异常组CRP无统计学意义差别,但均明显高于正常血糖组。结论炎症反应参与了糖尿病的发生发展,应在糖尿病前期开始进行干预措施,且糖尿病患者应平稳控制血糖。
Objective To study the levels of C-reactive protein in different glycometabolism states. Methods The turbidimetric method was used to determine CRP levels in chronic persistent hyperglycemia, chronic hyperglycemia, impaired fasting glucose, impaired glucose tolerance and normal blood glucose. Results The CRP in hyperglycemia group was significantly higher than that in persistent hyperglycemia group. There was no significant difference in CRP between fasting glucose group and impaired glucose tolerance group, but both were significantly higher than those in normal blood glucose group. Conclusion Inflammatory reaction is involved in the development of diabetes mellitus. Intervention should be started in pre-diabetes, and patients with diabetes should control blood sugar smoothly.