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新生血管形成是很多重要眼部疾病的共同病理改变,血管内皮细胞生长因子(vascular endothelial growth factor,VEGF)是新生血管形成过程中的关键性因子。近年来,抗VEGF药物的出现给新生血管性眼病的治疗开辟了新的途径。本文就近年来抗VEGF制剂在眼部新生血管性疾病的应用和副作用方面予以综述。
Neovascularization is a common pathological change in many important ocular diseases. Vascular endothelial growth factor (VEGF) is a key factor in neovascularization. In recent years, the emergence of anti-VEGF drugs opened up new avenues for the treatment of neovascular ophthalmopathy. This article reviews recent years the use of anti-VEGF agents in ocular neovascular diseases and their side effects.