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目的 研究生长抑素(SS)在豚鼠脑干听觉中枢的分布及意义。方法 采用免疫组化ABC法观察了豚鼠脑干听觉中枢的耳蜗核(CN)、上橄榄核簇(SOC)及下丘(IC)内SS免疫反应阳性产物的分布。结果 在脑干听觉中枢广泛分布着SS阳性神经元、纤维及终末。SS阳性神经元主要分布在蜗神经腹核(VCN)、斜方体核(NTB)、内侧上橄榄核(MSO)及橄榄周核(PON)，而SS阳性纤维及终末主要分布在下丘、外侧上橄榄核(LSO)及蜗神经背核(DCN)。结论 脑干听觉中枢内的SS参与声信号的传递与调控。
Objective To study the distribution and significance of somatostatin (SS) in the auditory central nervous system of guinea pig brainstem. Methods The distributions of cochlear nucleus (CN), superior olivary nucleus (SOC) and SS immunoreactive products in the inferior colliculus (IC) of guinea pig brainstem auditory center were observed by immunohistochemical ABC method. The results in the brainstem auditory center widely distributed SS positive neurons, fibers and terminals. SS positive neurons mainly distributed in VCN, NTB, MSO and PON, while SS positive fibers and terminal were mainly distributed in inferior colliculus, Lateral olives (LSO) and dorsal nucleus (DCN). Conclusion The SS involved in the brainstem auditory central nervous system is transmitted and regulated.