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目的 :探讨动态观察血清肌钙蛋白T对急性心肌梗塞的临床诊断和预后判断的意义。方法 :对 2 4例已确诊住院的心肌梗塞病人和 30例健康职工用酶联免疫测定法测定血清肌钙蛋白T。结果 :心肌梗塞病人在梗塞后血清肌钙蛋白T释放有两种曲线 ,即单峰性变化曲线和双峰性变化曲线。单峰性曲线的峰值为 11 37±8 1ug/L ,约在梗塞后 30～ 10 0小时出现 ;双峰性曲线的早期峰值 4 31± 4 30ug/L ,约在梗塞后 10～ 16小时出现 ,后期峰值 7 30± 3 34ug/L ,约在梗塞后 70～ 110小时出现。结论 :血清肌钙蛋白T是一项高度灵敏、高度特异反应的心肌损伤、心肌坏死的血清标态物 ,对心肌梗塞的诊断有重要意义。
Objective: To investigate the significance of dynamic observation of serum troponin T in clinical diagnosis and prognosis of acute myocardial infarction. Methods: Serum troponin T was measured by enzyme-linked immunosorbent assay in 24 cases of myocardial infarction patients and 30 cases of health workers who had been diagnosed as inpatients. RESULTS: There were two curves of serum troponin T release after myocardial infarction in patients with myocardial infarction: unimodal and bimodal curves. The peak value of unimodal curve was 11 37 ± 8 1ug / L, which was about 30 ~ 100 hours after infarction. The early peak of bimodal curve was 4131 ± 4 30ug / L, which appeared about 10 ~ 16 hours after infarction , The latter peak 7 30 ± 3 34ug / L, about 70 to 110 hours after infarction appear. CONCLUSION: Serum troponin T is a highly sensitive and highly specific response to myocardial injury. Serum markers of myocardial necrosis are important for the diagnosis of myocardial infarction.