论文部分内容阅读
氧氟沙星（ＯＦＬＸ）是最近研究、开发的新一代喹诺酮类广谱抗生素。笔者应用０．３％ＯＦＬＸ治疗耳部感染性疾病７９例、取得较好疗效，内以早期外耳道效果最佳，治愈率达１００％。次为急性化脓性中耳炎、痊愈率在成人组为９３％，儿童组１００％。慢性化脓性中耳炎疗效较差，成人组痊愈率为６６．６％，儿童组３３．３％；对葡萄球茵、大肠杆菌、铜绿色假单胞菌、阴沟杆菌、粪链球菌、臭鼻克雷伯氏菌的清除率均达１００％，奇异变形杆菌的清除率为５０％；对白细胞、红细胞、血红蛋白、血小板和听力均无明显影响；有４例于用药后出现暂时性轻度耳痛。
Ofloxacin (OFLX) is a new generation of quinolone broad-spectrum antibiotics recently researched and developed. The author applied 0.3% OFLX treatment of 79 cases of ear infections, and achieved good results, the best early external auditory canal, the cure rate of 100%. Secondary to acute suppurative otitis media, the cure rate was 93% in adults and 100% in children. The curative effect of chronic suppurative otitis media was poor. The cure rate of adult group was 66.6%, and that of children was 33.3%. The effects on Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Corynebacterium sp., Streptococcus faecalis, Leishmania were 100% clearance rate, Proteus mirabilis clearance rate was 50%; on white blood cells, red blood cells, hemoglobin, platelets and hearing had no significant effect; 4 cases of transient mild otolaryngitis after treatment .