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目的 :研究伽玛刀治疗脑胶质细胞瘤的临床疗效。方法 :自 1997年 5月至 2 0 0 0年 10月 ,对 139例脑胶质瘤患者进行伽玛刀治疗。男性 85例、女性 5 4例 ,年龄 5～ 77岁 ,平均 5 0岁。周边剂量 12～ 2 2 Gy,平均剂量 16 .5 Gy。结果 :治疗后随访个 6～ 31个月 ,30例影像学复查结果显示 :显效 7例 ( 2 3.3% ) ,有效 13例 ( 4 3.3% ) ,无变化 6例 ( 2 0 .0 % ) ,恶化 4例 ( 13.3% ) ,有效率为 6 6 .6 %。 6、 12、 2 4、 31个月存活率分别为 95 %、 81%、 47%、 33%。结论 :伽玛刀治疗脑胶质瘤疗效明确 ,可提高患者生存质量、延长生命。然而对恶性程度高的脑胶质瘤虽可控制肿瘤生长 ,但易复发 ,分次治疗可提高疗效
Objective: To study the clinical effect of gamma knife treatment of glioma. Methods: From May 1997 to October 2000, 139 patients with glioma were treated with gamma knife. 85 males and 54 females, aged 5 to 77 years, mean 50 years. Peripheral dose of 12 ~ 2 2 Gy, the average dose of 16.5 Gy. Results: The follow-up of 6 to 31 months after treatment showed that 7 cases (23.3%) were effective and 13 cases (4.3%) were effective in 6 cases (20.0%), In 4 cases (13.3%), the effective rate was 66.6%. The survival rates at 6, 12, 24, and 31 months were 95%, 81%, 47% and 33%, respectively. Conclusion: Gamma knife treatment of glioma clear effect, can improve the quality of life of patients and prolong life. However, the high degree of malignant gliomas can control tumor growth, but easy to relapse, sub-treatment can improve the efficacy