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作者对美国Ohio州立大学医学院外科1947～1994年已生存5年或死亡的74例(男45,女29)胃泌素瘤的材料进行分析。诊断时年龄17～74岁。8例为多发性内分泌肿瘤。61例有组织学报告,13例仅空腹胃泌素水平升高和促胰液素激发试验阳性而剖腹时未发现肿瘤。确诊为原发性60例(81％),自0.5～8.5cm大小。在14例未发现原发灶中1例肝转移。肿瘤位于胰腺36例,包括单个22例,多发性14例。原发位于十二指肠12例,包括单个22例,多发性14例。原发位于十二指肠12例,位于胃2例。7例同时有原发性胰和十二指肠肿瘤。另3例为胰外、肠外原发性肿瘤(淋巴结)。16例肝转移,其中7例伴淋巴结转移,13例仅淋巴结转移。全组分为1947
The authors analyzed the materials of 74 patients (45 males and 29 females) gastrinoma who had survived for 5 years or died from the surgery of the Ohio State University Medical School from 1947 to 1994. The age of diagnosis is 17 to 74 years old. Eight cases were multiple endocrine tumors. In 61 patients with histological reports, only 13 patients with elevated fasting gastrin levels and positive secretin challenge were positive and no tumors were found at laparotomy. It was diagnosed as primary 60 cases (81%), from 0.5 to 8.5cm in size. One case of primary liver lesions was not found in 14 cases. The tumors were located in 36 cases of pancreas, including 22 cases in a single case and 14 cases in multiple cases. The primary site was in the duodenum in 12 cases, including a single 22 cases and multiple cases of 14 cases. The primary site was in the duodenum in 12 cases and in the stomach in 2 cases. Seven patients had both primary pancreatic and duodenal tumors. The other 3 cases were extrapancreatic and extra-intestinal primary tumors (lymph nodes). 16 cases of liver metastases, of which 7 cases with lymph node metastasis, 13 cases of lymph node metastasis only. All components are 1947