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肥胖可改变肺功能。但目前的相关研究尚不能证明美国非洲裔(AA)、高加索裔(C)及拉美裔(H)肥胖妇女在肺活量、肺容积及弥散能力(DLCO)方面有何区别。而对其影响能力大小的评估往往由于其使用的引证方程不同而被混淆。因此,本研究的目的是探讨具不同背景的种族或族群肥胖妇女与肥胖相关的肺活量、肺容积及弥散能力,并使用各种不同而广泛使用的引证方程进行计算。本研究对40名美国非洲裔、25名高加索裔及15名拉美裔健康肥胖妇女(范围:超重的体脂肪在32%-55%之间)在体积描记器上进行了肺活量、肺容积及弥散能力的测定。用配对t检验和方差分析对引证方程进行了比较。用方程处理的各组年龄、血球容积、体重和基础代谢率相似;肺活量方面,即使观察到种族和族群间有较小的差别,但大致处于正常范围(FVC≈100%~115%;FEV1≈97%~107%);使用不同的引证方程计算,尽管总肺活量正常(≈98%~103%),但功能余气量偏低(≈75%~80%)或正常(≈90%~95%);无论用何种方程,余气量也是低的(≈60%~70%);肺弥散能力稍低(≈73%~91%);而DLCO/VA则正常(≈90%~110%)。我们的实验表明,肥胖对肺功能的影响独立于种族和族群的背景。在解释肺功能数据时应充分注意肥胖、种族和引证方程等方面的因素。
Obesity can change lung function. However, current research does not yet prove any difference in vital capacity, lung volume and diffusivity (DLCO) between obese women of African American (AA), Caucasian (C) and Hispanic origin. The assessment of the magnitude of their influence is often confused by the different citation equations used. Therefore, the purpose of this study was to investigate adiposity-related lung capacity, lung volume and diffusivity in racially or ethnically obese women with different backgrounds and to calculate them using a variety of widely used citation equations. In this study, spirometry, lung volume, and diffusion on a plethysmograph were performed on 40 American, African American, 25 Caucasian and 15 Hispanic healthy obese women (range: 32% -55% of overweight body fat) Determination of ability. The cited equations were compared using paired t-test and analysis of variance. Age, hematocrit, body weight, and basal metabolic rate were similar for each group treated with the equation; in terms of vital capacity, roughly normal range (FVC ≈100% -115%; FEV1 ≈3) was observed even though minor differences between races and ethnic groups were observed 97% -107%); using different citation equations, the functional residual capacity was low (≈75% -80%) or normal (≈90% -95%) despite the normal total lung capacity (≈98% -103% ); The residual gas volume was also low (≈60% -70%) regardless of the equation used; the lung diffusivity was slightly lower (≈73% -91%); DLCO / VA was normal . Our experiments show that the effects of obesity on lung function are independent of race and ethnic background. When interpreting pulmonary function data, pay due attention to factors such as obesity, race and citation equations.