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目的:调查我院临床治疗老年患者心律失常的用药习惯及合理性,为抗心律失常药临床合理应用提供数据。方法:利用《合理用药临床药学工作站》系统,在我院2009年1～12月住院明确诊断心律失常的老年患者中,筛选出使用口服抗心律失常药的病例,记录患者例数、年龄、心律失常临床表现、合并的主要疾病、药物使用方法、剂量等,依据相关资料进行用药合理性判断。结果:抗心律失常药比索洛尔、美托洛尔、美西律及普罗帕酮在治疗房颤、房性或室性早搏时多采用了较小剂量;药物的用法规范,尤其是胺碘酮,在治疗房颤时符合中华医学会心血管病学分会推荐的慢负荷方法;在用药的选择上虽然符合选用原则,但部分用药还缺乏大样本的临床循证医学依据。结论:我院老年患者抗心律失常药的运用基本合理。
Objective: To investigate the clinical practice and rationality of clinical treatment of arrhythmia in elderly patients in our hospital to provide data for the clinical application of antiarrhythmic drugs. Methods: The cases of oral anti-arrhythmic drugs were screened from elderly patients with in-hospital definite diagnosis of arrhythmia from January 2009 to December 2009 in our hospital. The number of patients, age, and heart rate Malfunction clinical manifestations, the main diseases combined, drug use, dosage, etc., based on the relevant information to determine the rationality of medication. Results: The anti-arrhythmic drugs bisoprolol, metoprolol, mexiletine and propafenone used more doses in the treatment of atrial fibrillation, atrial or ventricular premature beat. The usage of drugs, especially amiodarone Ketones, in the treatment of atrial fibrillation in line with the Chinese Society of Cardiology credits recommended slow load method; although the selection of medication in line with the selection principle, but some of the drug is still lack of large sample clinical evidence-based medicine. Conclusion: The use of antiarrhythmic drugs in elderly patients in our hospital is basically reasonable.