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４７例老年收缩期高血压患者经随机分组、尼群地平及安慰剂双盲对照治疗后，两组相比。治疗组血压控制满意、心血管并发症发生明显降低，且治疗组左室收缩功能及舒张功能均明显优于安慰剂组，表明尼群地平是适于老年收缩期高血压长期治疗的首选药物。
Forty-seven elderly patients with systolic hypertension were randomized to receive either nitrendipine or placebo after a double-blind, placebo-controlled study. Blood pressure in the treatment group was satisfactorily controlled and cardiovascular complications were significantly reduced. The left ventricular systolic function and diastolic function in the treatment group were significantly better than those in the placebo group, indicating that nitrendipine is the drug of choice for the long-term treatment of elderly systolic hypertension.