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氨基甙类抗生素抗菌谱广,使用方便,应用广泛,常见副作用是肾损害和耳毒性反应。近年随着药物在临床上的应用及观察,发现对该类药物的一些少见副作用,由于了解少而误诊,延误治疗,引起不良后果。医生和患者应对这些少见不良反应有所认识。 过敏性休克 见于特异性体质者,一般于肌注后5—10分钟出现胸闷、头晕、发热、四肢麻木,继之神志不清,血压可降至6千帕以下。一旦出现这些表现,应及时按过敏性休克的方案进行急救。 皮肤紫癜 紫癜多分布于四肢,对称、分批出现,颜色深浅不一,可凸出于皮肤,伴疼痒,检查可见皮肤划痕征阳性,血中白细胞及嗜酸粒细胞增多。对于这类皮肤紫癜须及时停药,给予相应止血、抗过
Aminoglycoside antibacterial spectrum wide, easy to use, widely used, common side effects are kidney damage and ototoxic reactions. In recent years, with the clinical application and observation of the drugs, some rare side effects of such drugs have been found. Due to less understanding and misdiagnosis and delayed treatment, adverse effects are caused. Doctors and patients should be aware of these rare adverse reactions. Anaphylactic shock seen in the specific constitution, generally 5-10 minutes after intramuscular injection chest tightness, dizziness, fever, numbness, followed by unconsciousness, blood pressure can be reduced to 6 kPa or less. In the event of these manifestations, prompt relief should be provided in an anaphylactic shock schedule. Skin Purpura Purpura are more distributed in the limbs, symmetrical, appear in batches, the color depth varies, can protrude from the skin, accompanied by itching, examination showed signs of skin scars positive, white blood cells and eosinophils increased. Purpura for these skin should be promptly discontinued, given the appropriate hemostasis, anti-over