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目的 探讨高血压及冠心病患者与高尿酸血症的相关性。方法 选择 1999年 12月至 2 0 0 1年 7月我院住院病人共 2 86例 ,入选病例分为 3组 :(1)单纯高血压病、无冠心病组 (T1组 ) 111例 ;(2 )高血压病合并冠心病组 (T2组 ) 10 4例 ;(3)单纯冠心病组 (T3组 ) 71例 ;(4 )另选无高血压、无冠心病、无糖尿病、无高脂血症者作为对照组 (T4组 ) 110例 ,分别检测血尿酸水平。结果 血尿酸水平 ,对照组 2 0 7.0 5± 93.6 9μmol/ L ,T1组 2 86 .97± 10 6 .4 9μmol/ L,T2组 2 77.86± 88.5 0 μmol/ L,T3组 2 84 .0 4± 119.71μmol/ L,与对照组相比 ,T1、 T2、T3组血尿酸水平明显增高 ,P值均 <0 .0 1,具有统计学意义。并且血尿酸水平与高血压病程呈正相关 r (111) =0 .35 0 ,P<0 .0 1;与年龄无相关性 r(111) =2 .84 9。结论 高血压病及 (或 )冠心病病人的血尿酸水平明显升高 ,高尿酸血症与高血压及冠心病密切相关
Objective To investigate the correlation between hypertension and coronary heart disease and hyperuricemia. Methods A total of 2 86 inpatients in our hospital from December 1999 to July 2001 were selected and divided into 3 groups: (1) 111 patients with simple hypertension without coronary heart disease (T1 group); ( 2) 104 patients with hypertension complicated with coronary heart disease (T2 group); (3) 71 patients with simple coronary heart disease (T3); (4) patients with no hypertension, no coronary heart disease, no diabetes, Serum as a control group (T4 group) 110 cases, respectively, the level of serum uric acid. Results Serum uric acid level in the control group was 20 7.0 5 ± 93.6 9 μmol / L, in the T1 group was 86.97 ± 106.49 μmol / L, in the T2 group was 77.86 ± 88.5 0 μmol / L, in the T3 group was 84.04 ± 119.71μmol / L, compared with the control group, serum uric acid levels were significantly increased in T1, T2, T3 group, P <0.01, with statistical significance. And serum uric acid levels and the course of hypertension was positively correlated r (111) = 0.35 0, P <0.01; no correlation with age r (111) = 2.84 9. Conclusions The level of serum uric acid in hypertensive patients and / or patients with coronary heart disease is significantly increased. Hyperuricemia is closely related to hypertension and coronary heart disease