论文部分内容阅读
本文报道了食物对红霉素乙基琥珀酸酯吸收的影响。18名志愿健康人员(14名男,4名女)年龄20—25岁,红霉素乙基琥珀酸酯为400g 薄膜片,按服药时间分为三组即(1)饭前即服800g,(2)饭后即服800mg,(3)饭后1小时服800mg。受试人员在试验前两周或研究中未接受其他抗生素或药物,给药前受试人员从午夜即开始禁食。标准早餐包括含牛乳的谷类食物,烤面包和果汁,15分钟内吃完。吃药时服水120ml,服药后的4小时内不给
This article reports the effect of food on erythromycin ethyl succinate absorption. 18 volunteers (14 males and 4 females) aged 20-25 years, erythromycin ethylsuccinate 400g film, according to medication time is divided into three groups that (1) 800g serving before meals, (2) serving 800mg after meals, (3) serving 800mg for 1 hour after meals. Subjects did not receive any other antibiotics or drugs for the first two weeks of the trial or during the study, and subjects were fasted from midnight prior to dosing. Standard breakfast includes cereal with milk, toast and juice, served in 15 minutes. Take medicine when serving water 120ml, do not give within 4 hours after taking medicine