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本文观察了各类肝病患者血浆脯肽酶活性的测定结果。肝硬化患者(21例)尽管ALT正常,但脯肽酶活性显著升高,异常率明显高于ALT;慢性活动性肝炎患者(11例)虽然脯肽酶与ALT均显著升高,但二者变化无明显相关,脯肽酶异常率明显高于ALT;急性肝炎患者(58例)脯肽酶与ALT均显著升高,二者变化呈正相关,脯肽酶恢复正常时间早于ALT。研究结果表明,血浆脯肽酶活性测定既是一项反映肝病慢性化,也是一项反映肝细胞损伤的良好指标。在评价脯肽酶作为肝病慢性化指标的意义时应首先除外急性肝损伤。
This article observed the plasma prolidase activity in patients with various types of liver disease measured results. In patients with cirrhosis (21 cases), although the ALT was normal, the procollagenase activity was significantly increased, the abnormal rate was significantly higher than that of ALT. Although the serum CP and ALT were significantly increased in 11 patients with chronic active hepatitis No significant correlation was found between the two groups. The abnormal rate of prolyl peptidase was significantly higher than that of ALT. The levels of procollagen and ALT were significantly increased in acute hepatitis patients (58 cases). The changes of both were positively correlated. The results showed that the determination of plasma procollagenase activity is not only a reflection of chronic liver disease, but also a good indicator of liver cell damage. In evaluating the significance of propeptidase as a marker of chronic disease in liver disease, acute liver injury should first be excluded.