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目的 :探讨伤痛外搽酊的活血祛瘀作用。方法 :采用耳廓微循环法测定了小鼠微血管管径和RBC流速 ;旋转玻璃株瓶法、比浊法测定了血小板粘附与聚集性 ;凝血酶原时间 (PT)法和优球蛋白溶解法测定了动物的PT和纤溶活性。结果 :伤痛外搽酊对肾上腺素所致血瘀模型之微血管具有明显扩张作用 ,并可加快微血管血流速度 ,对家兔血小板粘附性与聚集性具有显著抑制作用 ,且可延长凝血酶原时间和提高纤溶活性。结论 :伤痛外搽酊具有显著的活血祛瘀作用 ,其强度较正红花油稍好。
Objective : To explore the effect of blood stasis of external hemorrhoids. METHODS: Aortic microcirculation was used to measure the diameter of the microvessels in mice and RBC flow rate; platelet adhesion and aggregation were measured by rotating glass bottle method and turbidimetric method; prothrombin time (PT) method and euglobulin dissolution. The PT and fibrinolytic activities of the animals were measured. Results: Injury and external hemorrhoids have obvious expansion effect on the microvasculature of epinephrine-induced blood stasis model, and can accelerate the velocity of microvessel blood flow. It has a significant inhibitory effect on platelet adhesion and aggregation and can prolong thrombin. The original time and increased fibrinolytic activity. Conclusion : The external hemorrhoids have significant blood stasis effect and their strength is slightly better than that of safflower oil.