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目的探讨三维适形放疗治疗复发性卵巢癌患者的临床疗效。方法选取68例复发性卵巢癌患者,其中单纯化疗的31例患者为对照组,化疗联合三维适形放疗治疗的37例患者为观察组。观察两组病患治疗后的改善效果、生存时间以及毒性反应情况,并行统计学处理分析。结果观察组病例中总缓解率为40.5%,总获益率为64.8%,平均无进展生存时间为(6.5±0.9)个月,平均总生存期为(12.3±1.9)个月,与对照组相比差异均有统计学意义(P<0.05)。结论复发性卵巢癌患者应用三维适形放疗可显著提高临床疗效,延长生存时间,并不伴随显著的不良反应,值得广泛应用。
Objective To investigate the clinical efficacy of three-dimensional conformal radiotherapy in patients with recurrent ovarian cancer. Methods Seventy-eight patients with recurrent ovarian cancer were selected as the control group. Thirty-one patients in the chemotherapy group were treated as the control group, and 37 patients treated with chemotherapy combined with three-dimensional conformal radiotherapy were in the observation group. Two groups of patients were observed after treatment to improve the efficacy, survival time and toxicity, and statistical analysis. Results The total remission rate was 40.5% in the observation group, with a total benefit rate of 64.8%. The mean progression-free survival time was (6.5 ± 0.9) months and the average overall survival time was (12.3 ± 1.9) months. Compared with the difference was statistically significant (P <0.05). Conclusion The application of 3D conformal radiotherapy in patients with recurrent ovarian cancer can significantly improve the clinical efficacy, prolong the survival time, without significant adverse reactions, it is widely used.