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目的探讨获得性神经肌强直主要临床表现和电生理特征。方法回顾性分析3例获得性神经肌强直男性患者的临床和肌电图特点,并结合文献进行分析。结果 3例患者发病年龄21~64岁。3例患者均无中枢损害,其中2例表现为典型的骨骼肌游走性波浪状蠕动,另1例为肌肉疼痛、痉挛和肌无力、多汗。3例患者经电生理检查提示神经传导均正常,2例肌电图均可见特征性肌纤维颤搐表现。结论获得性神经肌强直主要表现为肌肉不自主颤搐、痉挛和假性肌强直,可合并多汗等植物神经损害表现。
Objective To investigate the main clinical manifestations and electrophysiological characteristics of acquired neuromuscular rigidity. Methods The clinical and electromyographic features of 3 patients with acquired neuromuscular dysplasia were retrospectively analyzed and analyzed according to the literature. Results 3 patients with onset age of 21 to 64 years. None of the 3 patients had central lesion. Two of them showed typical wavy motility of skeletal muscle migration. The other one was muscle pain, spasticity and muscle weakness, and hyperhidrosis. Electrophysiological examination revealed normal nerve conduction in 3 patients, and the appearance of myotonic twitching was observed in 2 cases of EMG. Conclusion Acquired neuromuscular ankylosis mainly manifested as autonomic twitching, spasms and pseudomyotonia, can be combined with hyperhidrosis and other autonomic nerve damage performance.