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采用直接荧光组织化学法对３００例女性乳腺癌进行三种性激素受体（雌激素受体ＥＲ、孕激素受体ＰＲ、雄激素受体ＡＲ）检测，结果ＥＲ、ＰＲ、ＡＲ阳性率分别为６１．６％、３８．３％和２２％．ＰＲ与ＥＲ阳性一致率为９８．３％，而ＡＲ与ＥＲ阳性一致率仅为５７．６％．本组结果显示乳腺癌硬癌性激素受体（ＨＲ）状况与年龄、肿瘤大小、组织学分级及腋淋巴结转移之间无相关性．而通常预后较差的非特殊型浸润性导管癌、单纯癌和ＨＲ阳性率高于其它各型乳腺癌，差异有显著性（Ｐ＜０．０５）．对４０例腋淋巴结转移癌ＨＲ检测结果表明，转移癌ＨＲ状况绝大多数与原发癌一致。
Three types of sex hormone receptors (ER, PR, and AR) were detected in 300 breast cancer patients by direct fluorescent histochemistry. The positive rates of ER, PR, and AR were 61. .6%, 38.3% and 22%. The positive rate of PR and ER was 98.3%, while the positive rate of AR and ER was only 57.6%. This group of results showed no correlation between sex hormone receptor (HR) status of breast cancer and age, tumor size, histological grade, and axillary lymph node metastasis. However, the positive rate of non-specific invasive ductal carcinoma, simple carcinoma and HR with poor prognosis is higher than that of other types of breast cancer. The difference is significant (P<0.05). The detection of HR in 40 cases of axillary lymph node metastases showed that the vast majority of metastatic cancer HR status was consistent with primary cancer.