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目的探讨腹部恶性纤维组织细胞瘤的诊治方法。方法回顾性分析28例腹部恶性纤维组织细胞瘤的临床表现、影像学特征、病理学特点、治疗方法、疗效和预后。结果 28例中 17例来源于腹膜后,6例来源于腹腔脏器,3例来源于肠系膜,2例来源于腹壁,主要临床表现为明显消瘦,体重减轻、腹痛和腹部肿块。B超和CT扫描提示腹部占位性病变。肿瘤≥2个24例,单发 4例。根治性切除17例,部分切除11例,术后联合化疗16例,联合放疗14例。术后1、3、5年生存率分别为76．9％,26．9％和3．9％。结论腹部恶性纤维组织细胞瘤主要来源于腹膜后,常多发,手术切除是首选的治疗方法,术后联合放化疗,可能改善患者预后。
Objective To investigate the diagnosis and treatment of malignant fibrous histiocytoma in the abdomen. Methods The clinical manifestations, imaging features, pathological features, treatment, efficacy and prognosis of 28 cases of malignant fibrous histiocytoma of the abdomen were analyzed retrospectively. Results Of the 28 cases, 17 cases were derived from the peritoneum, 6 cases originated from the abdominal organs, 3 from the mesentery and 2 from the abdominal wall. The main clinical manifestations were obvious weight loss, weight loss, abdominal pain and abdominal mass. B-scan and CT scan showed space-occupying lesions. Tumors> 2 in 24 cases, single in 4 cases. Radical resection in 17 cases, partial resection in 11 cases, postoperative combined chemotherapy in 16 cases, combined with radiotherapy in 14 cases. The 1, 3, 5-year survival rates were 76.9%, 26.9% and 3.9% respectively. Conclusion Malignant fibrous histiocytoma in the abdomen mainly comes from the retroperitoneal and often multiple operations. Surgical resection is the preferred method of treatment. Postoperative combined chemoradiotherapy may improve the prognosis of the patients.