Assessment of the Sensitivity and Specificity of the Established Real-time Quaking-induced Conversio

• 作 者: XIAO Kang YANG Xue Hua ZOU Wen
• 机 构: StateKeyLaboratoryforInfectiousDiseasePreventionandControl,CenterforGlobalPublicHealth,WuhanInstitut
• 出 处: 生物医学与环境科学:英文版
• 发表日期: 2020年8期
• 关键词: diagnosis CJD CEREBROSPINAL
• 基金项目: Supported by Chinese National Natural Science Foundation Grants[81630062,81572048],National Key Research and Development Project[2016YFC1202700,2017YFC1200500],the State Key Laboratory of Infectious D

Real-time quaking-induced conversion(RT-QuIC)assay is a newly established PrPSc-detecting method.The development of RT-QuIC improves the diagnosis of sporadic Creutzfeldt–Jakob disease(sCJD),showing good sensitivity and specificity in many countries when