论文部分内容阅读
目的观察米非司酮治疗更年期功血的临床疗效。方法将160例已诊断为更年期功血的患者随机分为治疗组与对照组,各80例,治疗组予米非司酮治疗,连续服药3个月,对照组予醋酸甲羟孕酮+己烯雌酚治疗,连服三周期。比较两组的临床疗效及性激素水平下降程度。结果治疗组的治愈率、P及E2的下降程度高于对照组,二者间差异有统计学意义(P<0.05),1年复发率低于对照组,二者间差异有统计学意义(P<0.05)。结论米非司酮治疗更年期功血时可获得较好的临床疗效。
Objective To observe the clinical efficacy of mifepristone in the treatment of climacteric dysfunctional uterine bleeding. Methods A total of 160 patients who had been diagnosed as menopause dysfunctional uterine bleeding were randomly divided into treatment group and control group, 80 cases each. The treatment group was given mifepristone for 3 months. The control group was given medroxyprogesterone acetate plus diethylstilbestrol Treatment, and even served three cycles. The clinical efficacy and levels of sex hormones were compared between the two groups. Results The cure rate, the decrease of P and E2 in the treatment group were higher than those in the control group (P <0.05), and the recurrence rate at 1 year was lower than that of the control group (P <0.05). The difference between the two groups was statistically significant P <0.05). Conclusion Mifepristone treatment of menopausal dysfunctional uterine bleeding can get better clinical efficacy.