细菌与乳腺癌的关系

• 作 者: 罗澜 陈创 李昕倩 孙圣荣
• 出 处: 国际肿瘤学杂志
• 发表日期: 2021年5期
• 关键词: 细菌 乳腺肿瘤 胃肠道微生物组

随着高通量测序等技术的应用，近年来研究发现，细菌不仅是乳腺炎等常见乳腺疾病的致病因素，还可能参与了乳腺癌的发生发展过程。乳腺内部组织中存在独特的细菌群落，它们的存在可能与乳腺癌的发病相关；近年研究发现，肠道菌群也可能通过调节雌激素等途径影响乳腺癌的患病率。进一步探索细菌对乳腺癌的影响，将为乳腺癌的诊断及治疗等提供新的思路。“,”With the application of high throughput sequencing and other technologies, in recent years people have found that bacteria are not only the causative factors of common breast diseases such as mastitis, but also may be involved in the occurrence and development of breast cancer. There are unique bacterial communities in the internal tissues of the breast, and their existence may be related to the incidence of breast cancer. Recent studies have found that intestinal flora may also affect the incidence of breast cancer by regulating estrogen and other pathways. Further exploration of the influence of bacteria on breast cancer will provide new ideas for diagnosis and treatment of breast cancer.