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目的:分析脓毒症患者肝功能损伤与病情严重程度及预后的相关性研究。方法:选取我院2016年3月~2017年4月收治的脓毒症患者120例作为研究对象,患者的肝功能变化以及APACHEII评分。结果:APACHEII评分越高,患者丙氨酸氨基转移酶,天门冬氨酸氨基转移酶,总胆红素,总胆汁酸的指标就会越高,但是清蛋白会降低,P<0.05表示统计学有意义。死亡组的患者在丙氨酸氨基转移酶,天门冬氨酸氨基转移酶,总胆红素,总胆汁酸以及APACHEII评分明显高于对照组,P<0.05表示统计学有意义。研究发现,肝功能障碍是影响脓毒症患者预后的主要影响因素。结论:肝功能的变化是表现脓毒症患者病情的关键指标,因此肝功能变化指标对判断脓毒症患者预后有重要意义。
Objective: To analyze the correlation between the severity of liver injury and prognosis in patients with sepsis. Methods: Seventy patients with sepsis who were treated in our hospital from March 2016 to April 2017 were selected as the study subjects. The changes of liver function and APACHEII scores of patients were analyzed. Results: The higher the APACHEII score, the higher the index of alanine aminotransferase, aspartate aminotransferase, total bilirubin, total bile acid, but the albumin will be reduced, P <0.05 means that the statistics Significant. Patients in the death group were significantly higher in the alanine aminotransferase, aspartate aminotransferase, total bilirubin, total bile acid and APACHEII scores, with a statistically significant P <0.05. The study found that liver dysfunction is the main factor affecting the prognosis of patients with sepsis. Conclusion: The change of liver function is the key index to show the condition of patients with sepsis. Therefore, the index of liver function is of great significance in judging the prognosis of patients with sepsis.