High mobility group box 1 protein (HMGB1) as an immune-modulating factor for polarization of human T

• 作 者: Lifeng Huang Yongming Yao Haid
• 机 构: DepartmentofMicrobiologyandImmunology
• 出 处: 老年心脏病学杂志：英文版
• 发表日期: 2008年2期
• 关键词: High MOBILITY group box-1 PROTEIN Immunity T LYMPHOCYTES Th1/Th2 High mobility g
• 基金项目: This study was supported by the National Natural Science Foundation of China (No. 30672178), National Basic Research Program of China (No. 2005CB522602),and the National Natural Science Outstanding Yo

Objective This study was performed to investigate the effect of high mobility group box-1 protein (HMGB 1) on immune function of human T lymphocytes in vitro and explore its potential role in cell-mediated immune dysfunction.Methods Fresh blood was obtain