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对1986年度确诊住院的52例甲状腺疾病病人(甲亢征30例,甲减征22例)和234例健康对照组的血清脂质、载脂蛋白进行了测定。结果证实甲状腺激素与脂质代谢有着密切的关系。特别是甲减病人,随着病情的加重,脂类代谢严重紊乱,甲状腺激素替代治.疗后,血脂(TC,TG)降低,脂蛋白胆固醇成份出现 HDL-ch 升高,LDL-ch 降低的变化,从而可望阻止动脉粥样硬化进展,甚至促进病变消退。文中探讨了用火箭电泳法测定 (?)poB 值的临床意义。
Serum lipids and apolipoproteins were measured in 52 cases of thyroid disease (thyroid hyperthyroidism in 30 cases, hypothyroidism in 22 cases) and 234 healthy controls diagnosed in 1986. The results confirmed that thyroid hormone and lipid metabolism are closely related. In particular, patients with hypothyroidism, with the aggravation of the disease, severe lipid metabolism disorders, thyroid hormone replacement therapy. After treatment, decreased blood lipid (TC, TG), lipoprotein cholesterol components increased HDL-ch, LDL-ch decreased Change, which is expected to stop the progress of atherosclerosis, and even promote regression of the disease. The paper discusses the rocket electrophoresis determination of (?) PoB value of clinical significance.