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目的：探究和分析重型颅脑外伤患者的护理体会。方法：选择我院接收的重型颅脑外伤患者50例为主要对象，所有患者均给予临床护理。结果：在依从性比较上，干预后患者优于干预前，P<0.05，提示有统计学意义；在生活质量比较上，干预后分值比干预前高，P<0.05，提示有统计学意义。结论：对重型颅脑外伤患者实施临床护理干预，能够有效提高患者的治疗依从性，改善患者的生活质量，值得普及。“,”Objective: To explore and analyze the nursing of patients with severe traumatic brain injury experience. Methods: Patients with severe craniocerebral injury in our hospital received 50 cases as the main object, al patients were given clinical nursing. Results: in the comparison of compliance, better than the patients before and after intervention, P<0.05, suggesting that there was statistical significance in comparison; quality of life, than pre intervention scores high, P<0.05, statisticaly significant hints. Conclusion: the implementation of clinical nursing intervention on patients with severe craniocerebral injury, and can effectively improve the treatment compliance of patients, improve the quality of life of patients, is worthy of popularization.