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目的：观察沙棘总黄酮对大鼠血浆ＰＧＩ２和ＴＸＡ２水平的影响。方法：采用放射免疫测定法，用１２５Ｉ标记血栓素Ｂ２和６酮前列腺素Ｆ１α放射免疫试剂盒测定。结果：１ｇ·ｋｇ－１剂量的沙棘总黄酮能非常显著地增加ＰＧＩ２的分泌，提高ＰＧＩ２／ＴＸＡ２的比值。结论：沙棘总黄酮具有单纯增强ＰＧＩ２分泌的作用。
Objective: To observe the effects of total flavonoids of Hippophae rhamnoides on levels of plasma PGI2 and TXA2 in rats. Methods: Radioimmunoassay was performed using 125I-labeled thromboxane B2 and 6 Keto-prostaglandin F1α radioimmunoassay kits. Results: 1 g·kg-1 dose of total flavonoids of sea buckthorn could significantly increase the secretion of PGI2 and increase the ratio of PGI2/TXA2. Conclusion: The total flavonoids of Hippophae rhamnoides can enhance the secretion of PGI2.