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目的：观察赛洛唑啉滴鼻液在鼻内镜检查中麻醉效果与传统1%地卡因+1%麻黄素麻醉效果，评价其临床应用价值。方法对来我院门诊行鼻内镜检查的206例患者（412侧鼻腔）分别给予左侧塞洛唑啉滴鼻液棉片于中鼻甲及下鼻甲表面麻醉，右侧给予传统1%地卡因+1%麻黄素棉片分别于中鼻甲及下鼻甲放置3min进行表面麻醉。观察双侧鼻甲收缩及鼻腔麻醉效果。结果麻醉满意度实验侧有效率为97.5%，对照侧有效率95.2%。鼻甲收缩情况实验侧有效率为90.9%；对照为69.3%。结论赛洛唑啉鼻用喷剂在治疗鼻炎的同时还具有显著表面麻醉作用，且副作用少，在鼻内镜检查中可替代传统地卡因+麻黄素，可有效避免地卡因及麻黄素致过敏性休克等严重不良反应的发生。“,”Objective To observe the anesthesia ef ect of xylometazoline nasal drops against the traditional 1%dicaine with 1%ephedrine under nasal endoscopy,then evaluate its clinical application value.Methods With nasal endoscopy in 206 patients (412 nasal cavities),the left side were given a piece of cot on with xylometazoline nasal drops in the middle turbinate and nasal turbinate surface, the right side were given a piece of cot on with the traditional 1%dicaine and 1%ephedrine in the middle turbinate and nasal turbinate anesthesia in 3 minutes into the surface.Observation on bilateral turbinate shrinkage and nasal anesthesia.Results The ef iciency of anesthesia satisfaction:the experimental side group is 97.5%,and the contrast side group is 95.2%.The ef iciency of turbinate shrinkage:the experimental side group was 90.9%,and the contrast side group is 69.3%.Conclusion Xylometazoline nasal spray in the treatment of rhinitis also has obvious ef ects on surface anesthesia with less side ef ects.It could substitute the traditional dicaine with ephedrine in nasal endoscopic examination,which could ef ectively avoid the occur ence of serious adverse reactions such as anaphylactic shock induced by dicaine and ephedrine.