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目的探讨手足口病重(危重)症患儿的临床观察与救治。方法回顾性分析开封市儿童医院PICU 262例重症手足口病患儿的流行病学特点、临床表现、实验室检查、治疗、转归等临床资料。结果重症患儿262例中危重症159例,合并呼吸系统受累239例,循环系统受累59例,在抗病毒治疗同时给予降颅压、呼吸、循环支持及丙种球蛋白、激素应用及对症治疗。治愈248例,留有后遗症9例,要求出院4例,死亡1例。结论早期筛查出重症患儿是提高救治成功的关键,重症患儿治疗原则是以脱水降颅压、激素、静脉用丙种球蛋白以及呼吸循环支持治疗为主的综合救治措施。
Objective To investigate the clinical observation and treatment of HFMD in children with HFMD. Methods A retrospective analysis of 262 children with PICU in Kaifeng City Children’s Hospital epidemiological characteristics of 262 patients with severe hand-foot-mouth disease, clinical manifestations, laboratory tests, treatment, prognosis and other clinical data. Results Among 262 critically ill children, 159 cases were critically endangered, 239 cases had respiratory system involvement, 59 cases had circulatory system involvement, and intracranial pressure, respiration, circulatory support, gamma globulin, hormones and symptomatic treatment were given concurrently with antiviral therapy. 248 cases were cured, leaving sequelae in 9 cases, requiring discharge in 4 cases and 1 case of death. Conclusion Early screening of critically ill children is the key to improve the success of treatment. The treatment of critically ill children is a comprehensive treatment based on dehydration and intracranial pressure, hormones, intravenous gamma globulin and respiratory circulation supportive therapy.