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目的探讨急性脑梗死患者血清C反应蛋白(CRP)与病情及预后的关系。方法测定65例急性脑梗死患者血清CRP含量,并与30名体检健康者进行对照,同时对急性脑梗死患者血清CPR水平与病情进行相关分析。结果脑梗死组血清CRP水平高于对照组(P<0.01);脑梗死不同临床分型间血清CRP水平比较,重型组高于中型、轻型组,差异均有显著性(P<0.05);脑梗死预后好转组CRP水平低于无好转组(P<0.05)。结论急性脑梗死患者血清CRP水平升高提示病情重、预后差;早期测定CRP水平有助于评估急性脑梗死的病情及预后。
Objective To investigate the relationship between serum C-reactive protein (CRP) and the prognosis of patients with acute cerebral infarction. Methods The serum levels of CRP in 65 patients with acute cerebral infarction were measured and compared with 30 healthy controls, and the serum levels of CPR in patients with acute cerebral infarction were analyzed. Results Serum levels of CRP in cerebral infarction group were significantly higher than those in control group (P <0.01). Serum CRP levels in different clinical types of cerebral infarction were higher than those in severe group (P <0.05) The CRP level in the improved prognosis group was lower than that in the control group (P <0.05). Conclusions The serum CRP level in patients with acute cerebral infarction is suggestive of serious illness and poor prognosis. The early determination of CRP level is helpful to evaluate the severity and prognosis of acute cerebral infarction.