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孕妇要注意用药,以防胎儿发育畸形,是众所周知的常识。但究竟有哪些药物能影响胎儿发育呢?下面就最常用的一些药物做一介绍。首先以抗生素最为多见,有氯霉素、四环素、链霉素、卡那霉素、庆大霉素、新霉素、灰黄霉素、制霉菌素、多粘菌素E、多粘菌素B、万古霉素、磺胺类、利福平、雷米封等。以四环素为例,常规剂量就可致胎儿牙齿、骨骼发育不良、牙釉质缺损、灰色牙、棕色牙或黄色牙及短肢畸形,先天性白内障等,大剂量还可诱发致命的肝脂肪变性。
Pregnant women should pay attention to medication to prevent fetal malformations, is a well-known common sense. But what drugs can affect fetal development? Here are some of the most commonly used drugs to make an introduction. First of all, the most common antibiotics, chloramphenicol, tetracycline, streptomycin, kanamycin, gentamicin, neomycin, griseofulvin, nystatin, polymyxin E, Prime B, vancomycin, sulfonamides, rifampicin, Remy sealed. Taking tetracycline as an example, conventional doses can cause fetal teeth, skeletal dysplasia, enamel defects, gray teeth, brown teeth or yellow teeth and short limb deformities, congenital cataracts, etc., and high doses can also induce fatal hepatic steatosis.