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目的 :观察MEBT治疗的深Ⅱ度烧伤创面的临床演变与病理变化 ,并探讨MEBT对深Ⅱ度创面的疗效.方法 :应用家兔深Ⅱ度烧伤模型 ,随机分MEBT组与对照组 (干疗组 ) ,观察伤后 1 ,3,5,7,1 0 ,1 5天及愈合后各时相点的临床特征及其病理变化.结果 :伤后 1天~ 3天 ,MEBT组与干疗组相比 ,创面湿润、渗出 ;之后 ,创面坏死组织由表及里地液化、脱落 ,至第 1 0天创面坏死组织液化殆尽 ,随之再生的“上皮岛”纵向生长 ,继而扩展、愈合.与之相应的病理变化进一步再现了上述过程.同时 ,MEBT组创面愈合时间明显缩短于干疗组 ,再生的皮肤质量好.结论 :MEBT治疗深Ⅱ度烧伤创面的疗效独特 ,而干疗组却不具备这些特点.“,”Objective: To observe the clinical evolution and pathological changes of deep second degree burn wound treated with MEBT and to investigage the effect of MEBT on the deep second degree burn wound.Methods:Rabbit model of deep second degree burn wound was used and animals were divided into MEBT group and control group randomly.Observations were made on the clinical characteristic and pathological changes on the first,third,fifth,seventh,tenth,fifteenth day post burn and after healing.Results:The burn wound in MEBT group became moist and exudative on 1-3 days post burn,followed by liquefaction and exfoliation of the necrotic tissue from surface into interior which lasted till the tenth day.Then the regenerated“skin islands”grew vertically and expanded to heal the wound.The corresponding pathological changes further reproduced the preceding process.At the same time,the time of wound healing in MEBT group was shortened significantly and the quality of regenerated skin was good.Conclusion:The effect of MEBT on deep second degree burn wound was particularly significant and quite different from that of dry therapy. [