强力霉素、920治疗大白鼠实验性气管炎的初步观察(摘要)

• 机 构: 四川医学院基础课程部,四川医学院病理学教研组 ,四川医学院药理学教研组,
• 出 处: 四川医学院学报
• 发表日期: 1973年02期
• 关键词: 强力霉素 大白鼠 气管炎 支气管炎症 病理检查 实验动物 硫磺粉 淋巴组织增生 摘要 临床症状

大白鼠65支,用硫磺粉、锯末、辣椒粉混合物烟熏,制造大白鼠气管炎模型。分为4组,分别从胃内灌注强力霉素、920、强力霉素+920、及蒸馏水作对照。观察临床症状及在不同时间处死作病理检查。实验给果:强力霉素治疗动物组三天后咳嗽鼠支明显减少,一个疗程后实验动物咳嗽基本停止。病理检查气管及支气管炎症改变较对照组及920组轻,上皮细胞及淋巴组织增生亦

65 rats were smoked with a mixture of sulphur powder, sawdust, and paprika to create rat bronchitis models. Divided into 4 groups, respectively, from the stomach perfusion doxycycline, 920, doxycycline + 920, and distilled water as a control. Observe the clinical symptoms and die at different times for pathological examination. The results of the experiment showed that after 3 days of doxycycline treatment in the animal group, coughing of the mouse branch was significantly reduced, and the cough of the experimental animal basically stopped after one course of treatment. The pathological changes of trachea and bronchial inflammation were lighter than those in the control group and the 920 group. Epithelial cells and lymphoid tissue hyperplasia were also observed.