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在大输液的质量检查中,热原检查是必须检验的一个项目,合格后方能使用。而引起人体发热的热原质有类固醇、细菌内毒素、病毒及其它微生物。这些物质中,细菌内毒素生物活性极强、不易被破坏去除,而其它致热物质在生产过程中或高压灭菌中被破坏、滤除或死亡,因此大输液涉及的热原反应主要是细菌内毒素的作用。目前热原检查方法有热原试验法即家兔法(Pyrogen Test,PT)和细菌内毒素检查法即鲎试验法(Limulus Test,
In the large infusion of quality inspection, pyrogen test is a project that must be tested before it can be used. The pyrogen causes the body fever steroids, bacterial endotoxin, viruses and other microorganisms. Among these substances, bacterial endotoxins are highly bioactive and are not easily destroyed and removed, while other pyrogenic substances are destroyed during the production process or autoclaved, filtered or killed, so the pyrogenic reactions involved in the large transfusion are mainly bacteria Endotoxin effect. At present, the pyrogen test method includes pyrogen test (PT) and bacterial endotoxin test (Limulus Test,