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对沈阳市区1991年4月至1994年12月的313例、年龄35~69岁的女性肺癌患者进行了按年龄配比1:1的病例对照研究。结果显示,女性肺癌的危险因素为吸烟、烹饪油烟暴露,其OR值与95%可信限分别为1.86(1.34~2.57)和4.31(3.07~6.05),其PAR%分别为22%与46%。吸烟与油烟对肺癌的发生有交互作用,其相对超额危险度为3.12。肺癌以腺癌为主,而吸烟仅与鳞癌有关。肺结核、慢性支气管炎增加肺癌发生危险性,但无显著意义。
A case-control study of 1:1 age-matched lung cancer patients aged 413 to 69 years old in Shenyang City from April 1991 to December 1994 was conducted. The results showed that the risk factors for female lung cancer were smoking and cooking fume exposure. Their OR and 95% confidence limits were 1.86 (1.34 to 2.57) and 4.31 (3.07 to 6.05), respectively. ) The PAR% were 22% and 46% respectively. There was an interaction between smoking and fumes on the occurrence of lung cancer, with a relative excess risk of 3.12. Lung cancer is mainly adenocarcinoma, and smoking is only related to squamous cell carcinoma. Tuberculosis and chronic bronchitis increase the risk of lung cancer, but it is not significant.