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应用高效液相色谱法测定５６ 例胃癌患者血浆ＡＡ 浓度，探讨了抗坏血酸（ＡＡ）与幽门螺杆菌感染（ＨＰ）及胃癌的关系。结果ＨＰ阳性胃癌患者血浆ＡＡ浓度明显低于ＨＰ阴性者（Ｐ＜ ０．００１），从而证明了ＨＰ感染造成ＡＡ降低与胃癌的发生密切相关。
The plasma AA concentration in 56 patients with gastric cancer was determined by high performance liquid chromatography and the relationship between ascorbic acid (AA) and Helicobacter pylori infection (HP) and gastric cancer was investigated. Results Plasma AA concentrations in HP-positive gastric cancer patients were significantly lower than those in HP-negative patients (P < 0.001), which proved that the reduction of AA caused by HP infection was closely related to the occurrence of gastric cancer.