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动物体外受精研究结果表明,精子抗体可干扰正常受精过程。在人类尚无精子自体抗体对受精全过程及随后卵裂影响资料的报道。本研究是通过不孕夫妇体外受精治疗结果的分析,获得人类的精子自体抗体对受精、胚胎分裂及以后妊娠发育的影响的有关资料。本组包括1980年～1984年接受体外受精的17对夫妇,男方有一次或多次血清精子制动试验(SIT)和/或精液免疫珠试验(IBT)阳性。大多数夫妇的体外精子与宫颈粘液的相互反应试验结果不良。这些试验通常在体外受精前12个月内进行,采用与体外受精时间最近的试验结果。126对SIT阴性的夫妇为对照组。精液标本在禁欲3至5天后用手淫法采取,射精后2小时内标本送至实验室,保存在
In vitro fertilization animal studies show that sperm antibodies can interfere with normal fertilization. No human sperm autologous antibodies on the whole process of fertilization and subsequent cleavage data reports. This study is based on the results of in vitro fertilization treatment of infertile couples to obtain information on the impact of human sperm autoantibodies on fertilization, embryonic division and subsequent pregnancy development. The group consisted of 17 couples who underwent in vitro fertilization between 1980 and 1984 who had one or more SITs and / or seminal immunobead tests (IBTs) positive. Most couples of in vitro sperm and cervical mucus reciprocity test results are not good. These tests are usually carried out within 12 months prior to in vitro fertilization, using the results of the test in the latest in vitro fertilization. 126 pairs of SIT-negative couple for the control group. Semen samples were taken 3 to 5 days after abstinence using masturbation method, 2 hours after ejaculation specimens sent to the laboratory, stored in