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目的:分析茵栀黄口服液治疗新生儿ABO溶血病的临床效果及安全性。方法:选择2014年1月至2014年9月期间我院收治的52例ABO溶血病患儿。将全部患儿随机分为观察组和对照组,每组各26例。对照组给予常规治疗,观察组在常规治疗的基础上,加用茵栀黄口服液进行治疗。比较两组患儿的治疗效果。结果:观察组光疗时间与黄疽消退时间均显著少于对照组,两组比较差异显著(P<0.05);治疗前两组患儿血清胆红素水平比较差异无统计学意义(P>0.05),而治疗24h,72 h后复查,观察组血清胆红素水平显著低于对照组,两组比较差异显著(P<0.05)。结论:在常规治疗的基础上加用茵栀黄口服液治疗新生儿ABO溶血症,能显著减轻黄疸的程度,缩短黄疸的持续时间,缓解患儿的临床症状,降低并发症的发生。
Objective: To analyze the clinical effect and safety of Yinzhihuang oral liquid in the treatment of neonatal ABO hemolytic disease. Methods: 52 children with ABO hemolytic disease admitted in our hospital from January 2014 to September 2014 were selected. All children were randomly divided into observation group and control group, with 26 cases in each group. The control group was given routine treatment. The observation group was treated with Yinzhihuang oral liquid on the basis of routine treatment. Compare the treatment effect of two groups of children. Results: The duration of phototherapy and the regression of jaundice in the observation group were significantly less than those in the control group (P <0.05). There was no significant difference in serum bilirubin between the two groups before treatment (P> 0.05 ), While the treatment 24h, 72h after the review, the observation group serum bilirubin levels were significantly lower than the control group, the two groups were significantly different (P <0.05). Conclusion: The addition of Yinzhihuang Oral Liquid to neonatal ABO hemolytic disease can reduce the degree of jaundice, shorten the duration of jaundice, relieve the clinical symptoms and reduce the incidence of complications on the basis of routine treatment.