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目的探究胃肠黏膜屏障功能障碍对患儿机体的影响。方法研究对象来自本院2011年1月~2013年12月收治的15例胃肠黏膜屏障功能障碍患儿(观察组)和15例无此功能障碍的患儿(对照组),比较两组患儿在观察期期间发生发热、感染等不良反应状况。结果患儿出现不良反应主要有发热反应、感染、脓毒症等不良反应,结果发现:观察组患儿出现不良反应发生率为40.00%,显著高于对照组患儿(6.67%),差异具有统计学意义(χ2=4.658,P=0.031)。结论胃肠黏膜屏障功能障碍易引起患儿临床症状出现发热、感染等不良症状,在临床中应该高度警惕胃肠黏膜屏障功能障碍等有可能引起的不良症状,有效预防以便能够减少患儿的不良症状发生。
Objective To investigate the effect of gastrointestinal mucosal barrier dysfunction on the body of children. Methods The subjects were from 15 children with gastrointestinal mucosal barrier dysfunction (observation group) and 15 children without this dysfunction (control group) admitted from January 2011 to December 2013 in our hospital. The patients in both groups were compared Children during the observation period fever, infection and other adverse reactions. Results Adverse reactions in children were mainly fever, infection, sepsis and other adverse reactions. The incidence of adverse reactions in the observation group was 40.00%, significantly higher than that in the control group (6.67%), the difference was Statistical significance (χ2 = 4.658, P = 0.031). Conclusion Gastrointestinal mucosal barrier dysfunction easily lead to clinical symptoms of children with fever, infection and other adverse symptoms, should be highly vigilant in the clinical gastrointestinal mucosal barrier dysfunction may cause adverse symptoms, effective prevention in order to be able to reduce the child’s poor Symptoms occur.