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目的:评价冠状动脉多支病变患者置入≥4枚国产药物洗脱支架(DES)的疗效。方法:2004-11至2006-11就诊于我科接受经皮冠状动脉介入治疗(PCI)的冠心病患者1127例,其中185例为置入支架≥4枚的多支病变患者,随访院内外主要心脏不良事件(MACE)包括心性死亡、急性心肌梗死和靶病变再次血运重建的发生率。结果:处理冠状动脉病变720处,其中复杂病变525处,置入国产DES836枚。院内1例高龄患者术后常规抗凝治疗死于脑出血,其余184例临床随访42(30～54)个月,发生急性心肌梗死4例,靶病变再次血运重建12例,院外MACE发生率8.6%。冠状动脉造影随访108例,DES边缘再狭窄5例,支架内再狭窄9例,再狭窄率13.0%。结论:冠状动脉多支病变患者置入≥4枚国产DES长期随访效果满意。
PURPOSE: To evaluate the efficacy of ≥4 homemade DES in patients with coronary artery disease. Methods: From November 2004 to November 2006, 1127 CHD patients undergoing percutaneous coronary intervention (PCI) were enrolled in our department. Among them, 185 patients were multi-vessel disease with stent ≥4, Cardiac adverse events (MACE) include the incidence of cardiac revascularization, acute myocardial infarction, and target revascularization. Results: 720 lesions of coronary artery were treated, of which 525 were complex lesions. One elderly elderly patient died of intracerebral hemorrhage after conventional anticoagulation therapy. The remaining 184 patients were followed up for 42 months (30-54 months) with acute myocardial infarction (n = 4) and target lesion revascularization (n = 12). The incidence of MACE outside hospital 8.6%. Follow-up coronary angiography in 108 cases, 5 cases of DES edge restenosis, 9 cases of stent restenosis, restenosis rate of 13.0%. Conclusion: Long-term follow-up of ≥4 homemade DES in patients with multi-vessel coronary disease is satisfactory.