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研究表明:红外热图在肿瘤的诊断和疗效评估方面有其独特的价值。本文对实验性肿瘤动物模型发生、发展过程进行了动态的红外热图、病理形态观察及血浆NO含量、组织微血管密度检测。以肝癌(H22)细胞接种于昆明小鼠后肢肌群建立肿瘤模型。实验小鼠随机分为两组:①肿瘤(Tu,n=88);②肿瘤对照组(Tc,n=88)。结果:血浆NO含量和组织微血管密度随小鼠肿瘤生长持续增高,且与肿瘤区平均温度值呈显著正相关。提示:NO含量增高,肿瘤区微血管密度增高是肿瘤局部高温可能原因。
Research shows that the infrared heat map has unique value in the diagnosis and therapeutic evaluation of tumors. In this paper, dynamic infrared thermograms, pathological observations, plasma NO content, and tissue microvessel density were detected in the development and progression of experimental tumor animal models. Hepatoma (H22) cells were inoculated into hind limb muscles of Kunming mice to establish a tumor model. The experimental mice were randomly divided into two groups: 1 tumor (Tu, n=88); 2 tumor control group (Tc, n=88). Results: The plasma NO content and tissue microvessel density continued to increase with the tumor growth in mice, and there was a significant positive correlation with the average temperature in the tumor area. Tip: The increase of NO content and the increase of microvessel density in the tumor area may be the reason for the high local tumor temperature.