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红细胞生成素(Epo)是肾脏对低氧血症反应而产生的一种糖蛋白类激素。慢性肾功能衰竭(CRF)贫血的主要原因是Epo 缺乏。在非肾脏疾病,血清Epo 增加是对贫血的反应,增加的量随贫血的病因不同而异.慢性疾病贫血(ACD),如在慢性感染,慢性炎症和恶性肿瘤患者的贫血,是一种轻度、非进行性贫血,且有血清铁减少而贮存铁过多的特点.其贫血的真正机理还不清楚。为了确定ACD 患者血清Epo 是否减低,作者将该类患者与贫血严重程度相似的单
Epo (erythropoietin) is a glycoprotein hormone produced by the kidney in response to hypoxemia. The main cause of chronic renal failure (CRF) anemia is Epo deficiency. In non-kidney disease, elevated serum Epo is a response to anemia and the increased amount varies with the cause of anemia. Chronic disease anemia (ACD), such as anemia in chronic infections, chronic inflammation, and malignancies, is a mild Degree, non-progressive anemia, and serum iron reduction and iron storage too much of its true mechanism of anemia is unclear. To determine if serum Epo was reduced in patients with ACD, the authors treated this group with a single