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探讨头颈部滤泡树突细胞肉瘤的临床病理特征及诊断、治疗方法。报道1例复发的右侧颈部滤泡树突细胞肉瘤41岁女性患者的临床资料。应用MEDLINE,以“树突细胞,肉瘤,滤泡状树突细胞”为主题词进行检索。对1986-01-2009-08发生于头颈部的滤泡树突细胞肉瘤并且有英文全文的文章进行分析总结。结果显示,成功手术切除右侧颈部复发的滤泡树突细胞肉瘤,术后予以放疗。通过MEDLINE检索共报道79例头颈部的FDCS患者,50.6%患者进行手术治疗,47.5%复发。21.5%患者进行了术后放疗,复发率35.3%。51.9%的患者复发后再手术和(或)放疗。CD21(+)和CD35(+)对淋巴滤泡树突细胞肉瘤的诊断有重要的意义。初步研究结果提示,淋巴滤泡树突细胞肉瘤是一种少见具有一定恶性倾向的肿瘤。外科手术加放疗是一种较好的治疗方法。
To explore the clinical and pathological features of the head and neck follicular dendritic cell sarcoma and its diagnosis and treatment. The clinical data of a 41-year-old woman with recurrent right-sided follicular dendritic cell sarcoma of the neck was reported. Use MEDLINE to “dendritic cells, sarcoma, follicular dendritic cells” as the keyword search. The articles about the follicular dendritic cell sarcoma in the head and neck from January 1986 to June 2009 with full text in English were analyzed and summarized. The results showed that successful surgical removal of the right side of the neck recurrence of follicular dendritic cell sarcoma, postoperative radiotherapy. A total of 79 patients with head and neck FDCS were reported by MEDLINE. Surgical treatment was performed in 50.6% of the patients, and 47.5% of them were relapsed. 21.5% patients underwent postoperative radiotherapy, the recurrence rate was 35.3%. 51.9% of patients relapsed after surgery and / or radiotherapy. CD21 (+) and CD35 (+) are important for the diagnosis of lymphoid follicular dendritic cell sarcoma. Preliminary findings suggest that lymphoid follicular dendritic cell sarcoma is a rare malignant tumor with a certain tendency. Surgery plus radiotherapy is a better method of treatment.