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目的研究深部热疗加同步放化疗方案在局部晚期宫颈癌中的临床效果。方法选取了我院2010年1月~2012年1月间入院治疗的80例晚期宫颈癌患者为研究对象,针对不同治疗方案的效果进行了比较分析。结果两组患者在实施不同治疗方法后,在近期治疗效果方面(1个月以后)试验组完全缓解(CR)32例,完全缓解率为80.00%;对照组完全缓解(CR)18例,完全缓解率为45.00%;在肿瘤局部控制情况方面试验组局部肿瘤完全消退30例,局部控制率为75.00%、对照组局部肿瘤完全消退20例,局部控制率为50.00%;在1年期无瘤生存情况方面试验组无瘤生存36例,无瘤生存率为90.00%、对照组无瘤生存24例,无瘤生存率为60.00%,差异有统计学意义(P均<0.05)。结论深部热疗加同步放化疗方案在局部晚期宫颈癌中的临床应用效果显著是晚期宫颈癌治疗中的一种安全有效的模式。
Objective To study the clinical effect of deep hyperthermia plus concurrent chemoradiotherapy in locally advanced cervical cancer. Methods Eighty patients with advanced cervical cancer admitted to our hospital from January 2010 to January 2012 were selected as the research objects, and the effects of different treatment regimens were compared and analyzed. Results Two groups of patients completed 32 cases of complete remission (CR) after complete treatment (1 month later), with a complete remission rate of 80.00% and 18 cases of complete remission (CR) in control group The remission rate was 45.00%. In the local control of tumor, the local tumor completely subsided in 30 cases and the local control rate was 75.00%. In the control group, the local tumor subsided completely in 20 cases and the local control rate was 50.00% Survival of the experimental group, 36 cases of tumor-free survival, tumor-free survival rate was 90.00%, 24 cases of tumor-free survival in the control group, tumor-free survival rate was 60.00%, the difference was statistically significant (P all <0.05). Conclusion The clinical effect of deep hyperthermia combined with concurrent chemoradiotherapy in locally advanced cervical cancer is significantly safe and effective in the treatment of advanced cervical cancer.