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本文对尿毒症并发心脏损害的临床表现、损害因素、机理、转归及预后加以分析。心脏扩大、心功能不全、奔马律、心脏收缩期杂音、心律失常，心包摩擦音是其主要临床表现。而尿毒症时数种毒素对心肌的特异性损害及高血压、贫血、代谢性酸中毒、电解质紊乱、感染等又是导致尿毒症性心脏病的主要因素。防止尿毒症性心脏病的有效措施是尿毒症早期采取血液净化疗法，减少血溶量，减轻心脏的前负荷，清除心脏毒性物质，防止心肌受损，从而达到改善尿毒症预后，降低病死率，延长寿命之目的。
This article analyzes the clinical manifestations, damage factors, mechanism, outcome and prognosis of uremia complicated with heart damage. Cardiac enlargement, cardiac insufficiency, galloping horse, systolic murmur, arrhythmia, pericardial frictional sound is its main clinical manifestations. While uremia several toxins on myocardial damage and specific damage to hypertension, anemia, metabolic acidosis, electrolyte imbalance, infection and so on are the main factors leading to uremic heart disease. Effective measures to prevent uremic heart disease is uremic early blood purification therapy to reduce blood volume, reduce the heart’s preload, remove cardiac toxic substances, prevent myocardial damage, so as to improve the prognosis of uremia, reduce mortality, The purpose of extending life expectancy.