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目的观察国产生物降解雷帕霉素药物洗脱支架(EXCEL)在冠状动脉分叉病变的近、中期疗效及安全性。方法回顾性分析郑州大学第一附属医院心血管科2009年2月至2010年2月57例分叉病变患者,主支均给予EXCEL支架,分支视情况给予血管球囊扩张或EXCEL支架,观察即刻手术成功率,术后9~12个月复查冠状动脉造影。结果手术即刻成功率为98.2%,住院期间无支架内血栓形成、急性心肌梗死或死亡等。冠状动脉造影随访,主支平均管腔丢失(0.12±0.04)mm,分支血管平均管腔丢失(0.15±0.06)mm,靶血管重建率5.3%。结论国产可降解药物洗脱支架治疗冠状动脉分叉病变安全有效。
Objective To observe the short-term and long-term efficacy and safety of domestic biodegradable rapamycin eluting stent (EXCEL) in the treatment of coronary bifurcation lesions. Methods A retrospective analysis of 57 patients with bifurcation lesions from February 2009 to February 2010 in Department of Cardiology of the First Affiliated Hospital of Zhengzhou University was given EXCEL stent. The branch was given balloon dilatation or EXCEL stent according to the situation. Surgical success rate, 9 to 12 months after coronary angiography. Results Immediate success rate was 98.2%. There was no stent thrombosis, acute myocardial infarction or death during hospitalization. Coronary angiography was followed up. The average loss of major lumen was (0.12 ± 0.04) mm. The mean loss of branch vessels was (0.15 ± 0.06) mm. The target vessel reconstruction rate was 5.3%. Conclusion Domestic biodegradable drug-eluting stents are safe and effective in treating coronary bifurcation lesions.